In silico evaluation of the toxicological profile of some molecules isolated from Aloe vera and watermelon (Citrullus lanatus) used in the formulation of sunscreens
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Abstract
Medical Cutaneous pharmacokinetics and toxicology are important in cosmetology, because the harmful effects of ultraviolet
light require external photoprotection, such as sunscreens containing sunscreens. However, some of these compounds are
toxic to the skin. As a result, natural plant-based products are increasingly being studied for their low toxicity. This study used
bioinformatics tools to assess the toxicity of six molecules, three from Aloe vera and three from watermelon. With the
exception of lycopene, all the molecules have a good toxicological profile. Computational approaches are presented are
presented as rapid and inexpensive tools for making predictions basis for future experimental studies.
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